If you are looking for a nice prototyping board featuring a PIC18F25K22 , I would take a look at the RADIX boards by Zardynamics. For very little money you get a nice breakout of all device pins (coincidentally compatible mechanically and electrically with a very large number of “shields” -duino style), but also ready to plugin the standard MCHP tool chain (ICSP single in line connector for the PICKIT3). There is a serial to USB bridge of course. The only thing missing at this point would seem to be a mikroBUS connector, so to play with a few Click© boards!? No need, there is a click-shield for that!
In 10 Lines of Code
Graphics, Touch, Sound, USB